Yarrowia production process
AssigneeDsm IP Assets B.V.
InventorsPeter Louis HOUSTON, Maria Elena MAYORGA, Valmik Kanubhai VYAS, Peter Scott YORGEY
Life of this patent
Estimating the term…
Abstract
The present invention is related to a novel process on biological production of lipophilic substances in an oleaginous host cell, particularly Yarrowia lipolytica, comprising modification in the N-glycosylation pathway, leading to higher yield and product purity with further facilitating the overall production process.
Claims14
A genetically modified host cell, particularly oleaginous yeast, accumulating intracellular lipophilic substances such as fat-soluble vitamins, carotenoids or polyunsaturated fatty acids (PUFAs), particularly carotenoids, said host cell comprising a mutation in an endogenous gene involved in the N-glycosylation pathway.
Dependencies are inferred from the claim text.