Compositions and methods for making and using small molecules in the treatment of cancer
AssigneeReglagene, Inc.
InventorsVijay Gokhale, Teri C. Suzuki
Life of this patent
Estimating the term…
Abstract
Embodiments of the instant disclosure relate to novel compounds, compositions, and methods for treating health conditions. In certain embodiments, methods of treating cancers can include administering an effective amount of at least one novel compound disclosed herein to a subject having cancer. In some embodiments, methods of treating cancers can include administering a pharmaceutical composition disclosed herein to a subject, the composition including at least one of the novel compounds disclosed herein, and optionally, one additional agent.
Claims7
-3. (canceled)
A compound according to formula (I),
- or formula (II),
- analogs, isomers, pharmaceutically acceptable salts, and prodrugs thereof:
- wherein:
- R1 and R6 are each independently selected from the group consisting of;
- R2 is selected from the group consisting of CH3 or F;
- wherein R3 and R7 are each a 5- or 6-membered heteroaryl unsubstituted or optionally substituted with one or more groups independently selected from the group consisting of alkyl, alkylamino, halogen, alkylhalide, cyano, cycloalkyl, heterocyclic alkyl, aryl, heteroaryl, cycloalkoxyl, heterocyclic alkoxyl, cycloalkylthio, and heterocyclic alkylthio,
- R4 and R5 are each independently selected from the group consisting of H and F;
- and
- R8 is selected from the group consisting of CH3 and H.
-9. (canceled)
A compound, wherein the compound is a compound according to Table 3.
A compound, wherein the compound is compound 19, compound 73, compound 86, compound 87, compound 88, compound 90, compound 91, compound 93, compound 94, compound 95, compound 96, compound 97, or compound 98.
-32. (canceled)
Dependencies are inferred from the claim text.