Method for determining acute toxicity and a system using said method
AssigneeCity University of Hong Kong
InventorsWenxiong WANG, Yiteng XIA
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Abstract
A method for determining acute toxicity of an analyte includes the steps of: a) exposing a first fish cell culture to a first reference solution; b) incubating the first fish cell culture in step a) with a fluorescent probe; c) obtaining a first fluorescence parameter from the stained first fish cell culture; d) establishing a first linear regression relationship model between the first fluorescence parameter and viability of an animal model; and e) determining acute toxicity of the analyte by adopting the first linear regression relationship model. A system using the method for determining acute toxicity of an analyte is also addressed.
Claims21
A method for determining acute toxicity of an analyte, comprising the steps of:
- a) exposing a first fish cell culture to a first reference solution;
- b) incubating the first fish cell culture in step a) with a fluorescent probe;
- c) obtaining a first fluorescence parameter from the stained first fish cell culture;
- d) establishing a first linear regression relationship model between the first fluorescence parameter and viability of an animal model;
- and
- e) determining acute toxicity of the analyte by adopting the first linear regression relationship model.
Dependencies are inferred from the claim text.