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US 2025/0092404 A1Published application
Pikfyve antisense oligonucleotides
AssigneeAcurastem Incorporated
InventorsWen-Hsuan CHANG, Emily Elizabeth LEE
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Abstract
The present invention relates to PIKFYVE antisense oligonucleotides (ASOs), pharmaceutical compositions containing them, and methods for treating, inhibiting, suppressing, and preventing neurological diseases with them.
Claims23
A single stranded antisense oligonucleotide of 20 nucleotides in length that suppresses the expression of a PIKFYVE, wherein the antisense oligonucleotide comprises a nucleobase sequence that comprises the sequence set forth in any of the nucleobase sequences of SEQ ID NOs:
- 1-500.
2-22. (canceled)
24-25. (canceled)
(canceled)
Dependencies are inferred from the claim text.