Next generation mrna vaccines
AssigneeFuTr Bio Ltda.
InventorsDaniel Santos MANSUR, André BÁFICA
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Abstract
Described herein are next generation vaccine compositions, including mRNA vaccines having flavivirus untranslated regions and vaccines comprising a (major histocompatibility complex) MHC binding peptide.
Claims42
A nucleic acid composition comprising a 5′ untranslated region (5′ UTR) of a first flavivirus, a 3′ untranslated region (3′ UTR) of a second flavivirus, a first polynucleotide encoding a first peptide that is exogenous to the first flavivirus and/or the second flavivirus, and a polynucleotide encoding a major histocompatibility complex (MHC) binding peptide.
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A nucleic acid composition comprising a 5′ untranslated region (5′ UTR) of a first flavivirus, a 3′ untranslated region (3′ UTR) of a second flavivirus, and a polynucleotide encoding a peptide, wherein the polynucleotide encoding the peptide is exogenous to the first flavivirus and/or the second flavivirus.
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A nucleic acid composition comprising a polynucleotide encoding a first peptide and a polynucleotide encoding a major histocompatibility complex (MHC) binding peptide.
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Dependencies are inferred from the claim text.