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US 2025/0090301 A1Published application
Device and method for preventing stenosis at an anastomosis site
AssigneeVascular Therapies, LLC
InventorsSriram Iyer, Gerald Dorros
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AssigneeVascular Therapies, LLC
InventorsSriram Iyer, Gerald Dorros
Estimating the term…
The present invention relates to treating or preventing stenosis at an anastomosis site. In one embodiment, the present invention is a stent is curved along the longitudinal axis for placement in and adjacent to the graft orifice. In a further embodiment, the stent is drug coated to allow delivery of antivasculoproliferative drugs directly to the vicinity of the graft orifice. In a further embodiment, the stent is expandable by use of an external wire. In another embodiment, the present invention is a kit comprising the specially configured stent together with a sleeve comprising a biocompatible matrix material and a pharmaceutical agent, wherein the sleeve is applied to the external surface of the vessel or graft, resulting in extravascular delivery of a pharmaceutical agent. Methods for treating or preventing stenosis at an anastomosis site by applying the extravascular sleeve and the intravascular stent are also provided.
A method for preventing or treating stenosis in a vascular structure having an anastomosis comprising deploying a drug free stent within the lumen of a vascular structure and applying locally and externally to the vascular structure, a biocompatible matrix material that carries an anti-vasculoproliferative drug and is free of biological cells, wherein the anastomosis is a part of an artery, vein or graft.
A method for preventing or treating stenosis at an anastomosis site comprising deploying a drug free stent within the lumen of a blood vessel and wrapping the exterior surface of the blood vessel with a biocompatible matrix material that carries an anti-vasculoproliferative drug and is free of biological cells.
A method for preventing or treating stenosis in a vascular structure having an anastomosis comprising deploying a drug free stent within the lumen of a vascular structure and applying locally and externally to the vascular structure a sleeve consisting essentially of a biocompatible matrix material and an anti-vasculoproliferative drug, wherein the anastomosis is a part of an artery, vein or graft.
Dependencies are inferred from the claim text.