# US 2025/0085237 A1 · Radiofrequency sensor system > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2025/0085237 A1 - Document ID: US20250085237A1 - Status: Published application - Kind: A1 - Application number: 18/882,568 - Filed: 2024-09-11 - Published: 2025-03-13 - Earliest claimed: 2023-09-13 - Assignees: Life Technologies Corporation - Applicants: Life Technologies Corporation - Inventors: Mark Thomas Smith; Ronald Abraham Martin; Brycen Hal Mills; Joshua Lynn Adams; Jia Zeng; Riley Baranowski - Web page: https://patentgrep.com/patent/US20250085237A1 ## CPC - G01N 22/00: Investigating or analysing materials by the use of microwaves or radio waves, i.e. electromagnetic waves with a wavelength of one millimetre or more (G01N3/00 - G01N17/00, G01N24/00 take precedence) - C12M 23/46: {Means for fastening} - C12M 41/32: {of substances in solution} - G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q) - C12M: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; {APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS} ## Abstract Devices, systems, and methods for measuring an analyte are disclosed. A device, system, or method can include a radiofrequency sensor comprising a radiofrequency transmitter and a radiofrequency receiver. A device, system, or method can be configured to transmit a radiofrequency signal from the transmitter to the receiver through a culture medium comprising the analyte. In some embodiments, a device, system, or method can include a controller configured to determine a concentration of the analyte based on a resultant signal produced at the receiver. A device, system, or method can comprise a radiofrequency sensor introducer. An introducer of a device, system, or method can comprise a first sensor sheath configured to receive a radiofrequency transmitter and a second sensor sheath configured to receive a radiofrequency receiver. In some implementations, an introducer of a device, system, or method can be configured to maintain a separation between the transmitter and receiver. ## Claims ### Claim 1 A system for measuring an analyte comprising: a radiofrequency sensor comprising a radiofrequency transmitter and a radiofrequency receiver, the sensor configured to transmit a radiofrequency signal from the transmitter to the receiver through a fluid comprising the analyte; and a controller comprising a processor and a non-transitory memory in communication with the sensor, the non-transitory memory comprising instructions that, when executed, cause the processor to determine a concentration of the analyte based on a resultant signal produced by the receiver. ### Claim 2 (depends on 1) The system of claim 1, wherein determining the concentration of the analyte comprises determining a change in radiofrequency signal amplitude between the radiofrequency signal transmitted by the transmitter and the radiofrequency signal received by the receiver, at one or more transmission frequencies. ### Claim 3 (depends on 2) The system of claim 2, wherein the one or more transmission frequencies comprises a range of frequencies of from 1 Hz to 10 GHz, from 1 Hz to 9 GHz, from 1 Hz to 8 GHz, from 1 Hz to 7 GHz, from 1 Hz to 6 GHz, from 1 Hz to 5 GHZ, 1 Hz to 4 GHz, from 1 Hz to 3 GHz, from 1 Hz to 2 GHz, from 1 Hz to 1 GHz, from 25 MHz to 10 GHz, from 25 MHz to 9 GHZ, from 25 MHz to 8 GHZ, from 25 MHz to 7 GHZ, from 25 MHz to 6 GHz, from 25 MHz to 5 GHZ, 25 MHz to 4 GHz, from 25 MHz to 3 GHZ, from 25 MHz to 2 GHz, or from 25 MHz to 1 GHz. ### Claim 4 (depends on 1) The system of claim 1, wherein the controller is configured to cause the transmitter to transmit the radiofrequency signal through the fluid. ### Claim 5 (depends on 1) The system of claim 1, further comprising: a bioprocess container comprising the fluid, wherein the radiofrequency transmitter in direct contact with a first portion of the bioprocess container, and the radiofrequency receiver is in direct contact with a second portion of the bioprocess container. ### Claim 6 (depends on 5) The system of claim 5, wherein the radiofrequency transmitter is directly coupled to the first portion of the bioprocess container using an adhesive or a fastener. ### Claim 7 (depends on 5) The system of claim 5, wherein the radiofrequency receiver is directly coupled to the second portion of the bioprocess container using an adhesive or a fastener. ### Claim 8 (depends on 5) The system of claim 5, wherein the first portion of the bioprocess container directly opposes the second portion of the bioprocess container. ### Claim 9 (depends on 5) The system of claim 5, wherein the first portion of the bioprocess container is a first wall of the bioprocess container. ### Claim 10 (depends on 5) The system of claim 5, wherein the second portion of the bioprocess container is a second wall of the bioprocess container. ### Claim 11 (depends on 5) The system of claim 5, wherein the first portion of the bioprocess container and the second portion of the bioprocess container are separate portions of one wall of the bioprocess container. ### Claim 12 (depends on 1) The system of claim 1, further comprising: a bioprocess container comprising the fluid, wherein the radiofrequency transmitter and the radiofrequency receiver are not in direct contact with the bioprocess container. ### Claim 13 (depends on 12) The system of claim 12, further comprising a housing having one or more cavities defined at least in part by one or more walls of the housing. ### Claim 14 (depends on 13) The system of claim 13, wherein the one or more cavities are shaped and sized to receive at least a portion of the bioprocess container. ### Claim 15 (depends on 12) The system of claim 12, wherein the radiofrequency transmitter is directly coupled to a first wall of the one or more walls. ### Claim at position 16 16-49. (canceled) ### Claim 50 A method for measuring an analyte, the method comprising: transmitting a radiofrequency signal from a radiofrequency transmitter into a fluid comprising an analyte; receiving a resultant radiofrequency signal at a radiofrequency receiver, wherein the resultant radiofrequency signal is the transmitted radiofrequency signal after it has passed through at least a portion of fluid; and analyzing the radiofrequency signal received by the receiver to determine a concentration of the analyte in the fluid. ### Claim 51 (depends on 50) The method of claim 50, wherein the fluid is comprised in a bioprocess container and wherein the radiofrequency transmitter in direct contact with a first portion of the bioprocess container and the radiofrequency receiver is in direct contact with a second portion of the bioprocess container. ### Claim 52 (depends on 51) The method of claim 51, wherein the radiofrequency transmitter is directly coupled to the first portion of the bioprocess container using an adhesive or a fastener. ### Claim 53 (depends on 51) The method of claim 51, wherein the radiofrequency receiver is directly coupled to the second portion of the bioprocess container using an adhesive or a fastener. ### Claim 54 (depends on 50) The method of claim 50, wherein the first portion of the bioprocess container directly opposes the second portion of the bioprocess container. ### Claim at position 22 55-126. (canceled)