Biosynthesis of sulfur-containing compounds using genetically modified bacteria

A genetically modified prokaryotic cell which comprises a vanin (vnn) polynucleotide sequence selected from the group consisting of:

• a vanin-1 (vnn1) polynucleotide sequence which has at least 70% sequence coverage to SEQ 3 or SEQ 69, and at least 70% sequence identity to SEQ 3 or SEQ 69;
• a vanin-2 (vnn2) polynucleotide sequence which has least 70% sequence coverage to SEQ 70, and at least 70% sequence identity to SEQ 70;
• and
• a vanin-3 (vnn3) polynucleotide sequence which has least 70% sequence coverage to SEQ 111, and at least 70% sequence identity to SEQ 111.

A genetically modified prokaryotic cell which comprises:

• a cysteamine dioxygenase (ado) polynucleotide sequence which has at least 70% sequence coverage to SEQ 1, and at least 70% sequence identity to SEQ 1;
• and
• a vanin (vnn) polynucleotide sequence selected from the group consisting of:
• a vanin-1 (vnn1) polynucleotide sequence which has at least 70% sequence coverage to SEQ 3 or SEQ 69, and at least 70% sequence identity to SEQ 3 or SEQ 69;
• a vanin-2 (vnn2) polynucleotide sequence which has at least 70% sequence coverage to SEQ 70, and at least 70% sequence identity to SEQ 70;
• and
• a vanin-3 (vnn3) polynucleotide sequence which has at least 70% sequence coverage to SEQ 111, and at least 70% sequence identity to SEQ 111.

A genetically modified prokaryotic cell which comprises:

• a cysteamine dioxygenase (ADO) polypeptide sequence which has at least 70% sequence coverage to SEQ 2, and at least 25% sequence identity to SEQ 2;
• and
• a vanin (VNN) polypeptide sequence selected from the group consisting of:
• a vanin-1 (VNN1) polypeptide sequence which has at least 70% sequence coverage to SEQ 4, and at least 25% sequence identity to SEQ 4;
• a vanin-2 (VNN2) polypeptide sequence which has at least 70% sequence coverage to SEQ 84, and at least 25% sequence identity to SEQ 84;
• and
• a vanin-3 (VNN3) polypeptide sequence which has at least 70% sequence coverage to SEQ 128 and at least 25% sequence identity to SEQ 128.