# US 2025/0082879 A1 · Respiratory assistance device and a method of controlling said device > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2025/0082879 A1 - Document ID: US20250082879A1 - Status: Published application - Kind: A1 - Application number: 18/784,728 - Filed: 2024-07-25 - Published: 2025-03-13 - Earliest claimed: 2013-03-15 - Assignees: Fisher & Paykel Healthcare Limited - Applicants: Fisher & Paykel Healthcare Limited - Inventors: Stanislav Tatkov; Kevin Peter O'Donnell - Web page: https://patentgrep.com/patent/US20250082879A1 ## CPC - A61M 16/0069: {the speed thereof being controlled by respiratory parameters, e.g. by inhalation} - A61M 15/009: {using medicine packages with incorporated spraying means, e.g. aerosol cans (pocket atomiser of the injector type A61M11/08)} - A61M 16/0003: {Accessories therefor, e.g. sensors, vibrators, negative pressure} - A61M 16/024: {including calculation means, e.g. using a processor} - A61M 16/0666: {Nasal cannulas or tubing (devices for improving normal breathing through the nose A61F5/08; nose filters A62B23/06; outside holding devices A61M25/02)} - A61M 16/0875: {Connecting tubes} - A61M 16/104: {specially adapted for anaesthetics (A61M16/18 takes precedence)} - A61M 16/12: by mixing different gases - A61M 16/122: {with dilution} - A61M 16/16: Devices to humidify the respiration air {(A61M16/1045 takes precedence)} - A61M 16/1015: {using a gas flush valve, e.g. oxygen flush valve} - A61M 2016/0027: {pressure meter} - A61M 2016/003: {with a flowmeter} - A61M 2016/0039: {in the inspiratory circuit} - A61M 2202/0208: Oxygen - A61M 2202/0225: Carbon oxides, e.g. Carbon dioxide - A61M 2202/0241: Anaesthetics; Analgesics - A61M 2205/3334: Measuring or controlling the flow rate - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract A method of controlling a flow rate of gases supplied to a patient by a respiratory assistance device includes controlling the supply gases flow rate so as to deliver gases to the patient according to a predetermined gases pressure/flow rate profile for at least a portion of the breathing cycle. A profile may be achieved that provides the patient with a particular benefit or therapy. ## Claims ### Claim 1 (canceled) ### Claim 2 A respiratory assistance device comprising a flow generator, the flow generator being configured to generate a flow of respiratory gases to be delivered to a patient, the flow generator being in fluid communication with a humidifier, the humidifier being configured to increase a humidity level of the flow of respiratory gases, the flow generator and the humidifier being operatively coupled to a controller configured to provide variable nasal high flow therapy, the controller controlling the flow generator to provide a first flow profile such that an inspiratory pressure is substantially constant during an inspiratory phase, the controller also controlling the flow generator to provide a second flow profile such that an expiratory pressure is higher during an expiratory phase compared to the inspiratory pressure during the inspiratory phase. ### Claim 3 (depends on 2) The respiratory assistance device of claim 2, wherein the expiratory pressure during the expiratory phase is substantially constant in the second flow profile. ### Claim 4 (depends on 3) The respiratory assistance device of claim 3, wherein the second flow profile comprises a varying flow rate during the expiratory phase to maintain the expiratory pressure substantially constant. ### Claim 5 (depends on 2) The respiratory assistance device of claim 2, wherein the controller controls the flow generator to increase flow rate at an end of the inspiratory phase or at a start of the expiratory phase. ### Claim 6 (depends on 2) The respiratory assistance device of claim 2, wherein the controller controls the flow generator to steadily reduce flow rate during the expiratory phase from a first flow rate to a second flow rate, wherein the first flow rate is higher than the second flow rate. ### Claim 7 (depends on 6) The respiratory assistance device of claim 6, wherein, between the inspiratory phase and the expiratory phase, the controller controls the flow generator to significantly increase flow rate. ### Claim 8 (depends on 7) The respiratory assistance device of claim 7, wherein, between the inspiratory phase and the expiratory phase, the controller controls the flow generator to substantially linearly increase flow rate to the first flow rate. ### Claim 9 (depends on 2) The respiratory assistance device of claim 2, wherein the controller controls the flow generator to maintain a pressure of 1 cm H2O during the inspiratory phase. ### Claim 10 (depends on 2) The respiratory assistance device of claim 2, wherein the controller controls the flow generator to maintain a pressure of 4 cm H2O or more during the expiratory phase. ### Claim 11 (depends on 2) The respiratory assistance device of claim 2, wherein flow rate is reduced during the inspiratory phase from an initial inspiratory flow rate to an end inspiratory flow rate. ### Claim 12 (depends on 11) The respiratory assistance device of claim 11, wherein the initial inspiratory flow rate is 60 L/min and the end inspiratory flow rate is 20 L/min. ### Claim 13 (depends on 2) The respiratory assistance device of claim 2, wherein pressure is maintained at alternating values of 1 cm H2O and 5 cm H2O during a respiratory cycle while delivering variable nasal high flow therapy. ### Claim 14 (depends on 2) A respiratory system comprising the respiratory assistance device of claim 2 and a nasal interface, the nasal interface being fluidly connected to the respiratory assistance device with an inspiratory tube. ### Claim 15 (depends on 14) The respiratory system of claim 14, wherein the nasal interface is a nasal cannula. ### Claim 16 (depends on 14) The respiratory system of claim 14, wherein the nasal interface comprises a hybrid nasal interface where leakage is not high. ### Claim 17 (depends on 14) The respiratory system of claim 14, wherein flow during inspiration is higher than during expiration. ### Claim 18 A respiratory assistance device comprising: a flow generator configured to generated a flow of respiratory gases that will be delivered to a patient; a humidifier being in fluid communication with the flow generator; a controller being operatively coupled to the flow generator and the humidifier, the controller being configured to provide variable nasal high flow therapy, the controller being programmed to control the flow generator to create a first flow profile with an inspiratory pressure that is substantially constant during an inspiratory phase, the controller also being programmed to control the flow generator to create a second flow profile with an expiratory pressure that is higher during an expiratory phase compared to the inspiratory pressure during the inspiratory phase, a pressure sensor or a flow sensor being located within the respiratory assistance device, the controller being programmed to detect the inspiratory phase and the expiratory phase based on a pressure or flow reading from the pressure sensor or the flow sensor respectively; and an inspiratory tube being in fluid communication with the humidifier, the inspiratory tube being configured to deliver gases to the patient, and the inspiratory tube comprising a heater.