# US 2025/0082243 A1 · Systems, devices, and methods for electrophysiological recording from the eye > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2025/0082243 A1 - Document ID: US20250082243A1 - Status: Published application - Kind: A1 - Application number: 18/883,162 - Filed: 2024-09-12 - Published: 2025-03-13 - Earliest claimed: 2023-09-12 - Assignees: Retmap, Inc. - Applicants: Retmap, Inc. - Inventors: John R. Hetling - Web page: https://patentgrep.com/patent/US20250082243A1 ## CPC - A61B 5/398: Electrooculography [EOG], e.g. detecting nystagmus; Electroretinography [ERG] - A61B 5/251: Means for maintaining electrode contact with the body - A61B 5/26: maintaining contact between the body and the electrodes by the action of the subjects, e.g. by placing the body on the electrodes or by grasping the electrodes - A61B 5/297: for electrooculography [EOG]: for electroretinography [ERG] - A61B 5/6821: {Eye} - A61B 2562/0209: Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053 - A61B 2562/16: Details of sensor housings or probes; Details of structural supports for sensors (A61B2560/0462 takes precedence) - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract Systems, devices, and methods for electrophysiological recording from the eye are disclosed herein. An electroretinography device can detect a biopotential signal from an eye of a subject and transmit the same to a processor. Embodiments of the present technology include one or more features directed to improving the use and operability of an electroretinography device. For example, the device can include a proximal inner surface having a recess feature for removing or receiving fluids trapped between the device and the eye. The recess feature can include one or more grooves, channels or textured surface designed to collect and direct fluids away from the space between the device and the eye. The number, shape, size, position, orientation, and other features of the grooves and channels can be varied. ## Claims ### Claim 1 An electroretinography device configured to detect a biopotential signal from an eye of a subject, the device comprising: an ocular member including: a proximal portion comprising a proximal outer surface extending radially inward along a distal direction and a proximal inner surface opposite the proximal outer surface, wherein, when the ocular member is disposed over the eye, the proximal inner surface is disposed over an anterior surface of the eye and the proximal outer surface is positioned adjacent an eyelid of the subject, wherein the proximal inner surface includes a recess feature configured to receive tears from the eye; and a distal portion coupled to the proximal portion, wherein the distal portion comprises a distal outer surface extending radially outward in the distal direction, and a distal inner surface opposite the distal outer surface and defining at least in part a distal recess; a conductive element in an annular channel of the proximal portion; and a signal relay operatively connected to the conductive element and configured to transmit the biopotential signal from the conductive element to a signal processor. ### Claim 2 (depends on 1) The device of claim 1, wherein the recess feature comprises at least one groove extending along the inner surface. ### Claim 3 (depends on 1) The device of claim 1, wherein the recess feature comprises at least one groove extending along the proximal inner surface, and wherein the proximal outer surface of the proximal portion is smooth and/or does not include a groove. ### Claim 4 (depends on 1) The device of claim 1, wherein: the proximal inner surface includes a cornea portion and a sclera portion at a proximal-most edge extending radially around the cornea portion, the sclera portion has a first cross-sectional dimension and the cornea portion has a second cross-sectional dimension smaller than the first cross-sectional dimension, and the recess feature comprises at least one groove extending along the inner surface from the sclera portion to the cornea portion. ### Claim 5 (depends on 1) The device of claim 1, wherein the recess feature comprises at least five linear grooves spaced apart from one another along the proximal surface. ### Claim 6 (depends on 1) The device of claim 1, wherein the recess feature comprises a plurality of circular and/or concentric grooves extending along the proximal inner surface. ### Claim 7 (depends on 1) The device of claim 1, wherein the recess feature comprises a first groove extending radially along the proximal inner surface and a second concentric groove extending around the proximal inner surface. ### Claim 8 (depends on 1) The device of claim 1, wherein the recess feature comprises a first concentric groove extending along the proximal inner surface, and a second concentric groove extending along the proximal inner surface that is proximal to the first concentric groove. ### Claim 9 (depends on 1) The device of claim 1, wherein the recess feature comprises a plurality of circular grooves parallel to and concentric with the annular channel of the proximal portion. ### Claim 10 (depends on 1) The device of claim 1, wherein the recess feature comprises a series of adjacent grooves that form an undulating surface. ### Claim 11 (depends on 1) The device of claim 1, wherein the recess feature comprises a plurality of channels extending through the proximal portion from the proximal outer surface to the proximal inner surface. ### Claim 12 (depends on 1) The device of claim 1, wherein the recess feature comprises a plurality of channels extending through the proximal portion from the proximal outer surface to the proximal inner surface, and wherein the channels are spaced apart from an axis extending through a center of the ocular member by at least 4 millimeters. ### Claim 13 (depends on 1) The device of claim 1, wherein the recess feature comprises a plurality of channels extending through the proximal portion from the proximal outer surface to the proximal inner surface, and wherein the channels are arranged around the proximal portion in a predetermined pattern. ### Claim 14 (depends on 1) The device of claim 1, wherein the recess feature has a cross-sectional shape of a rectangle, circle, semicircle, or triangle. ### Claim 15 (depends on 1) The device of claim 1, wherein the recess feature comprises a texture across the proximal inner surface. ### Claim 16 (depends on 1) The device of claim 1, wherein: the proximal inner surface includes (i) a cornea portion, (ii) a sclera portion at a proximal-most edge extending radially around the cornea portion, and (iii) a transition zone extending between the sclera portion and the cornea portion, and the sclera portion has a first cross-sectional dimension and the cornea portion has a second cross-sectional dimension smaller than the first cross-sectional dimension. ### Claim 17 An electroretinography device, the device comprising: a proximal portion comprising a proximal outer surface extending radially inward along a distal direction and a proximal inner surface opposite the outer surface, wherein the proximal inner surface is configured to be disposed over an anterior surface of an eye of a subject, wherein the proximal outer surface is configured to be positioned adjacent an eyelid of the subject, wherein the proximal portion includes recess features configured to receive tears from the eye, the recess features including a first recess feature and a second recess feature spaced apart from the first recess feature; and a distal portion coupled to the proximal portion, wherein the distal portion comprises a distal outer surface. ### Claim 18 (depends on 17) The device of claim 17, wherein the recess features are configured to direct the tears received from the eye to a proximal-most edge of the proximal surface along radial directions. ### Claim 19 (depends on 17) The device of claim 17, wherein at least one of the first recess feature or the second recess feature comprise a circular groove configured to trap the tears received from the eye. ### Claim 20 (depends on 17) The device of claim 17, wherein (i) the first recess feature comprises a linear groove configured to direct the tears received from the eye proximally toward a proximal-most edge of the proximal surface along radial directions and (ii) the second recess feature comprises a circular groove configured to trap the tears received from the eye. ### Claim 21 (depends on 17) The device of claim 17, wherein the recess features extend radially around the proximal inner surface. ### Claim 22 (depends on 17) The device of claim 17, wherein the first recess feature comprises a channel on the proximal inner surface and configured to direct the tears received from the eye through the proximal portion along a direction non-parallel to the distal direction, wherein the proximal outer surface does not include the recess features. ### Claim 23 (depends on 17) The device of claim 17, wherein: the proximal inner surface includes a cornea portion and a sclera portion at a proximal-most edge extending radially around the cornea portion, the sclera portion has a first cross-sectional dimension and the cornea portion has a second cross-sectional dimension smaller than the first cross-sectional dimension, and at least one of the first recess feature or the second recess features comprise a channel configured to direct the tears received from the eye through the proximal portion from the sclera portion. ### Claim 24 (depends on 17) The device of claim 17, wherein: the proximal inner surface includes a cornea portion and a sclera portion at a proximal-most edge extending radially around the cornea portion, the sclera portion has a first cross-sectional dimension and the cornea portion has a second cross-sectional dimension smaller than the first cross-sectional dimension, and at least one of the first recess feature or the second recess feature comprise a channel configured to direct the tears received from the eye through the proximal portion from the cornea portion. ### Claim 25 (depends on 17) The device of claim 17, wherein: the proximal inner surface includes a cornea portion and a sclera portion at a proximal-most edge extending radially around the cornea portion, the sclera portion has a first cross-sectional dimension and the cornea portion has a second cross-sectional dimension smaller than the first cross-sectional dimension, and at least one of the first recess feature or the second recess feature comprise a texture across the proximal inner surface exclusive of the cornea portion. ### Claim 26 (depends on 17) The device of claim 17, wherein the distal portion further comprises a distal inner surface opposite the distal outer surface and defining at least in part a distal recess.