O-phosphoserine-producing microorganism and method for producing o-phosphoserine or l-cysteine using the same
AssigneeCj Cheiljedang Corporation
InventorsHwi-Min JUNG, Jin Ah RHO, Hee-jin SIM, Hye Min PARK
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Abstract
The present application relates to a microorganism in which an activity of erythronate-4-phosphate dehydrogenase is weakened; a method for producing O-phosphoserine, cysteine, or cysteine derivatives using the microorganism; a composition for producing O-phosphoserine comprising the microorganism; and the use of the microorganism in the production of O-phosphoserine, cysteine, and cysteine derivatives.
Claims10
An O-phosphoserine-producing microorganism, in which an activity of erythronate-4-phosphate dehydrogenase is weakened.
A method for producing O-phosphoserine, comprising culturing an O-phosphoserine-producing microorganism, in which an activity of erythronate-4-phosphate dehydrogenase is weakened, in a medium.
A method for producing cysteine or a derivative thereof, comprising:
- a) culturing an O-phosphoserine-producing microorganism, in which an activity of erythronate-4-phosphate dehydrogenase is weakened, in a medium to produce O-phosphoserine or a medium containing the same;
- and
- b) reacting O-phosphoserine sulfhydrylase (OPSS) or a microorganism expressing the same;
- O-phosphoserine produced in step a) or a medium containing the same;
- and a sulfide.
Dependencies are inferred from the claim text.