Sea urchin-derived peptide and use thereof
AssigneeNational Marine Biodiversity Institute of Korea
InventorsSeon Mi Jo, Seung Hyun Jung, Hye Suck An, Jei Ha Lee, Kyung Hwa Baek, Hea Bin Kim, Ha Jeong Lee
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AssigneeNational Marine Biodiversity Institute of Korea
InventorsSeon Mi Jo, Seung Hyun Jung, Hye Suck An, Jei Ha Lee, Kyung Hwa Baek, Hea Bin Kim, Ha Jeong Lee
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The present invention relates to a sea urchin-derived peptide and a use thereof and more specifically, to a use of the sea urchin-derived peptide for preventing or treating a disease associated with the V1B receptor of Echinotocin, which is a peptide derived from sea urchins. The Echinotocin according to the present invention was found to have an effect of inducing activation of the V1B receptor, which is a type of vasopressin receptors. The V1B receptor, which is a vasopressin receptor, exists in the anterior pituitary gland and the hippocampus CA2 region and is known to increase intracellular calcium concentration and to be involved in a response to stress and sociality. Therefore, the Echinotocin according to the present invention can find various applications in the field of preventing, alleviating, or treating V1B receptor-related diseases.
A pharmaceutical composition for preventing or treating V1B receptor-related diseases, comprising a peptide represented by an amino acid sequence set forth in SEQ ID NO:
A food composition for preventing or alleviating V1B receptor-related diseases, comprising a peptide represented by an amino acid sequence set forth in SEQ ID NO:
A method for treating V1B receptor-related diseases, comprising administering a peptide represented by an amino acid sequence set forth in SEQ ID NO:
Dependencies are inferred from the claim text.