Method of treating hypogonadism in men

A method of treating hypogonadism in a human male patient, the method comprising the steps of:

• determining a first total serum testosterone level of the patient;
• if the patient's first total serum testosterone level is below about 500 ng/dL, starting the patient on an initial dosage amount of about 140 mg of a testosterone androstane steroid derivative (TASD), administered about every 7 days;
• after four consecutive TASD administrations, determining a second total serum testosterone level, an estrogen level, and a hemoglobin level of the patient;
• if after four consecutive TASD administrations, the estrogen level is elevated, starting the patient on about 1 mg anastrozole, administered about once weekly:
• if after taking the 1 mg anastrozole administered about once weekly the patient has a low estrogen level, decreasing the anastrozole dosage to about 0.5 mg, administered about once weekly;
• if after the four consecutive TASD administrations the patient has an elevated hemoglobin level, starting the patient on aspirin, administered daily;
• if after the four consecutive TASD administrations, the second total serum testosterone level is within a therapeutic/stabilized range and the four consecutive TASD administrations are therapeutically effective, continuing the patient on the initial dosage amount of the TASD;
• if after the four consecutive TASD administrations, the second total serum testosterone level is above the therapeutic/stabilized range, decreasing the initial dosage amount of TASD by about 20 mg;
• if after the four consecutive TASD administrations, the second total serum testosterone level is below the therapeutic/stabilized range, increasing the initial dosage amount of TASD by about 20 mg.