# US 2025/0067656 A1 · Element for an optical measurement system

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- Number: US 2025/0067656 A1
- Document ID: US20250067656A1
- Status: Published application
- Kind: A1
- Application number: 18/722,074
- Filed: 2022-12-16
- Published: 2025-02-27
- Earliest claimed: 2021-12-20
- Assignees: Diagdev
- Applicants: Diagdev
- Inventors: Benoit, Georges, Gérard MERCHEZ
- Web page: https://patentgrep.com/patent/US20250067656A1

## CPC

- G01N 15/1436: {the optical arrangement forming an integrated apparatus with the sample container, e.g. a flow cell}
- G01N 21/0303: {Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment (G01N21/031 - G01N21/15 take precedence)}
- G01N 21/05: Flow-through cuvettes (G01N21/09 takes precedence; handling fluid samples G01N1/10)
- G01N 2015/1452: {Adjustment of focus; Alignment}
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)

## Abstract

An element for optical measurement system including a first crown extending circumferentially around an axis and including at least one first optical lens, and a second crown located radially outside of the first crown and surrounding the first crown and including at least one second optical lens where at least one first lens is aligned with at least one second lens, the first and second crowns are made of the same material so as to form a unitary element.

## Claims

### Claim at position 1

1-13. (canceled)

### Claim 14

An element for optical measurement system comprising a first crown extending circumferentially around an axis and comprising at least one first optical lens, and a second crown located radially outside of the first crown and surrounding the first crown and comprising at least one second optical lens where at least one first lens is aligned with at least one second lens, the first and second crowns are made of the same material so as to form a unitary element, said element comprising centering or alignment means located near at least one second lens and intended to engage with additional centering or alignment means of an optical emitter or receiver, and said element further comprising a calibrated passage opening, intended for the passage of a flow comprising a sample to be analyzed, located and oriented along said axis of the first and second crowns and opening out in a space delimited by the first crown and forming a measurement chamber through which said fluid is intended to pass.

### Claim 15 (depends on 14)

The element according to claim 14, characterized in that said calibrated opening is cylindrical with a circular base and has a diameter included between 30 and 100 μm.

### Claim 16 (depends on 14)

The element according to claim 14, wherein said calibrated opening is provided in a thin wall of the same material as said first and second crowns, said thin wall having a thickness included between 10 and 80 μm.

### Claim 17 (depends on 14)

The element according to claim 14, wherein at least one first lens may be aspheric type.

### Claim 18 (depends on 14)

The element according to claim 14, wherein at least one second lens may be spheric type.

### Claim 19 (depends on 16)

The element according to claim 16 further comprising an upstream chamber, located across from the measurement chamber relative to the thin wall.

### Claim 20 (depends on 14)

A measurement system comprising an element according to claim 14, at least one optical emitter, and at least one optical receiver, mounted facing a second lens.

### Claim 21 (depends on 20)

The system according to claim 20, further comprising means for bringing a fluid containing a sample to be characterized into the upstream chamber, where said fluid passes through the calibrated opening and opens into the measurement chamber.

### Claim 22 (depends on 21)

The system according to claim 21, further comprising means for bringing a first sheath fluid near the upstream chamber.

### Claim 23 (depends on 21)

The system according to claim 21, further comprising means for bringing a second sheath fluid near the measurement chamber.

### Claim 24 (depends on 21)

The system according to claim 21, further comprising an interference filter facing at least one second lens, mounted on said element, radially between the first and second crowns.

### Claim 25 (depends on 21)

The system according to claim 21, further comprising an achromatic doublet mounted on the element and arranged facing an optical emitter and a lens of the first crown.

### Claim 26 (depends on 21)

The system according to claim 21, further comprising at least two electrodes, located axially on either side of the calibrated opening, and measurement means suited for measuring an impedance between said electrodes.