A system for delivering a synchronized cardiopulmonary resuscitation (CPR), configured to ensure delivery of an efficient amount of oxygen to essential organs whilst prevent cerebral hypocapnia by maximizing delivery of carbon dioxide to a brain, comprises:
- (a) at least one limb compression device, configured for exerting a distal-to-proximal sequential compression force onto a limb and for occluding a blood flow into said limb, wherein said compression force is exerted constantly and not intermittently;
- (b) a positive-pressure ventilation sub-system, configured for delivering a mixture of gases by positive pressure, comprising:
- (I) a carbon dioxide reservoir containing a carbon dioxide enriched gas;
- (II) a molecular oxygen reservoir containing a molecular oxygen enriched gas;
- (III) a controllable mixing module, operationally connected to said carbon dioxide reservoir and said molecular oxygen reservoir, configured to controllably mix said molecular oxygen enriched gas with said carbon dioxide enriched gas;
- (IV) at least one carbon dioxide partial pressure sensor selected from the group consisting of:
- an arterial blood carbon dioxide partial pressure sensor and end-tidal exhaled air carbon dioxide partial pressure sensor, configured to detect a partial pressure of carbon dioxide in an arterial blood;
- (V) a controller, operationally connected to said controllable mixing module and said at least one carbon dioxide partial pressure sensor, configured for controlling at least one ratio selected from the group consisting of:
- a ratio of said molecular oxygen enriched gas and ratio of said carbon dioxide enriched gas, in a mixture of said molecular oxygen enriched gas and said carbon dioxide enriched gas;
- wherein said controller is configured to include an efficient amount of said molecular oxygen in said ratio of said mixture of said molecular oxygen enriched gas and said carbon dioxide enriched gas, and
- wherein said controller is further configured to increase an amount of said carbon dioxide enriched gas in said ratio of said mixture of said molecular oxygen enriched gas and said carbon dioxide enriched gas, thereby maximizing delivery of carbon dioxide to a brain and preventing cerebral hypocapnia;
- (VI) an endotracheal tube comprising a unidirectionally sealing cuff disposed at a distal portion of said endotracheal tube, configured for iteratively and intermittently assuming:
- (i) a deployed configuration, wherein said unidirectionally sealing cuff is engaged to an interior surface of a trachea, thereby effectively sealing a passage of gasses in-between said unidirectionally sealing cuff and said interior surface of a trachea, whilst sustaining an inflow of gases from said endotracheal tube, into said trachea;
- wherein said deployed configuration is assumed by said unidirectionally sealing cuff during an inhaling phase of a respiratory cycle;
- (ii) a withheld configuration, wherein said sealing cuff is disengaged from said interior surface of said trachea, whilst sustaining a spontaneous outflow of said gases from said trachea;
- wherein said withheld configuration is assumed by said unidirectionally sealing cuff during an exhaling phase of said respiratory cycle;
- (c) a cardiac stimulation device, configured for returning a spontaneous circulation of said arterial blood, by providing at least one type of stimulation to a cardiac muscle, selected from the group consisting of:
- a mechanical stimulation and electrical stimulation, at a predetermined time intervals;
- (d) an intra-tracheal pressure sensor configured for continuously determining a pressure inside said trachea;
- (e) a synchronizer configured for timing an injection phase of said positive-pressure ventilation system with an onset of a decompression phase of said cardiac stimulation.