Drug delivery systems based on endoperoxides useful in diagnosis and therapy, and methods thereof

A compound of formula I, including enantiomers and racemic mixtures thereof, wherein:

• R1 and R2 are independently hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl and substituted or unsubstituted heteroaryl,
• R1 and R2 may be joined to form a substituted or unsubstituted cycloalkyl and substituted or unsubstituted heterocycloalkyl
• X is —CH2O—, —OCH2— or —O—O—
• R3 is —C(R4)(R5)—, —CH(R4)—CH(R5)— or —C(R4)═C(R5)—
• R4 is hydrogen, —OH, —CH2OH, —CH2O(C═O) A or —CH2O(C═S)A, wherein A is independently one or more API, proteins and antibodies for inflammation, diabetes, cardiovascular disease, malaria, orphan diseases, neurodegenerative disorders, infectious diseases and cancer diagnosis and treatment
• R5 and R6 are independently hydrogen, —OH, —O(C═O)A or —O(C═S)A, wherein A is independently one or more API, proteins and antibodies for inflammation, diabetes, cardiovascular disease, malaria, orphan diseases, neurodegenerative disorders, infectious diseases and cancer diagnosis and treatment,