A method performed by a first radio unit, RU, of a distributed base station system, the first RU comprising N1 antennas, the distributed base station system further comprising a first aggregation unit, AU, connected to the first RU via a first AU fronthaul, FH, link and a second RU connected to the first AU via a second AU FH link, the second RU comprising N2 antennas, the distributed base station system further comprising a baseband unit, BBU, connected to the first AU over a first BBU FH link, the method comprising:
- receiving, at the N1 antennas and from a first number of UEs, uplink, UL, data streams comprising first user layers K1 of the first number of UEs;
- obtaining a first uplink, UL, channel estimate Ĥ1 of a communication channel between the first number of UEs and the first RU;
- determining first intermediate beamforming weights, BFW, C1 to be used for centralized interference mitigation, based on the first UL channel estimate Ĥ1;
- sending, to the first AU, at least a part of the determined first intermediate BFW C1;
- and
- obtaining first part of BFW WRU1 based on the first UL channel estimate Ĥ1.