Calibrating a mass spectrometer

Abstract

A method of calibrating a mass spectrometer is disclosed, the mass spectrometer comprising at least one ion detector of a first type having a first ion intensity measurement range (IDR1) and at least one ion detector of a second type having a second ion intensity measurement range (IDR2). The first ion intensity measurement range and the second ion intensity measurement range share an overlap range (IDR0). The method may comprise: —detecting a wash period (WP), —measuring, during and/or following a wash period, an ion intensity using both at least one ion detector of a first type and at least one ion detector of a second type to produce a first measured ion intensity and a second measured ion intensity respectively, and —using the first measured ion intensity and a second measured ion intensity to determine a detector calibration factor.

Dependencies are inferred from the claim text.