Tms protocol and assessment

A system for determining an efficacy of a transcranial magnetic stimulation (TMS) treatment protocol, comprising:

• a control circuitry, wherein the control circuitry is configured to:
• analyzing EEG signals recorded during a TMS treatment delivered to a patient, to generate values of one or more EEG parameters;
• determining an acute effect and/or an intermediate effect of the TMS protocol on a brain state of the patient based on a change in values of the one or more EEG parameters;
• and
• determining an efficacy of a TMS protocol used in the TMS treatment based on the determined acute effect and the determined intermediate effect.

A method for determining an efficacy of a transcranial magnetic stimulation (TMS) treatment, comprising:

• delivering TMS to a patient using a TMS protocol in a TMS treatment session;
• recording EEG signals before and after the delivering during the treatment session;
• recording EEG signals after completion of the treatment session;
• analyzing the recorded EEG signals to generate values of one or more EEG parameters;
• determining an acute effect and an intermediate effect of the TMS protocol on a brain state of the patient based on a change in values of the one or more EEG parameters;
• determining an efficacy of the TMS protocol based on the determined acute effect and the intermediate effect.

A method for determining an efficacy of a transcranial magnetic stimulation (TMS) treatment, comprising:

• delivering TMS to a patient using a TMS protocol as part of a treatment session;
• recording EEG signals before and after the delivering during the treatment session;
• analyzing the recorded EEG signals to generate values of one or more EEG parameters;
• determining an acute effect of the TMS protocol on a brain state of the patient based on values of the one or more EEG parameters;
• performing a cognitive examination of the patient using at least one cognitive exam, after completing the treatment session to determine an intermediate effect of the TMS protocol, and
• determining an efficacy of the TMS protocol based on the determined acute effect and the determined intermediate effect.