Sialic acid compositions for use in inhibiting and treating infections in fish
AssigneeLifeScience AS
InventorsJan Remmereit, Trond-inge Kvernevik
Life of this patent
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Abstract
The present invention relates to the use of compositions comprising sialic acid to improve the health of fish in aquaculture, and in particular to inhibit or treat viral infections in fish, improve growth, and to inhibit or treat infestation of fish with sea lice.
Claims87
A method for treating or inhibiting infection by Infectious Salmon Anemia Virus (ISAV), in fish in aquaculture, the method comprising:
- administering a composition comprising sialic acid or precursor thereof in an effective concentration to the fish under conditions such that infection by ISAV is treated.
A method for prophylaxis of infection by ISAV, in fish in aquaculture, the method comprising:
- administering a composition comprising sialic acid or precursor thereof in an effective concentration to the fish under conditions such that infection by ISAV is inhibited.
A method for treating or inhibiting infection by Salmon Pancreas Disease Virus (SPDV), in fish in aquaculture, the method comprising:
- administering a composition comprising sialic acid or precursor thereof in an effective concentration to the fish under conditions such that infection by SPDV is treated.
A method for prophylaxis of infection by SPDV, in fish in aquaculture, the method comprising:
- administering a composition comprising sialic acid or precursor thereof in an effective concentration to the fish under conditions such that infection by SPDV is inhibited.
A method for treating or inhibiting infection by sea lice, in fish in aquaculture, the method comprising:
- administering a composition comprising sialic acid or precursor thereof in an effective concentration to the fish under conditions such that infection by sea lice is treated.
A method for prophylaxis of infection by sea lice, in fish in aquaculture, the method comprising:
- administering a composition comprising sialic acid or precursor thereof in an effective concentration to the fish under conditions such that infection by sea lice is inhibited.
A method for treating or inhibiting infection by Infectious Pancreatic Necrosis Virus (IPNV), in fish in aquaculture, the method comprising:
- administering a composition comprising sialic acid or precursor thereof in an effective concentration to the fish under conditions such that infection by IPNV is treated.
A method for prophylaxis of infection by IPNV, in fish in aquaculture, the method comprising:
- administering a composition comprising sialic acid or precursor thereof in an effective concentration to the fish under conditions such that infection by IPNV is inhibited.
A method for treating or inhibiting infection by Piscine Orthoreovirus (PRV), in fish in aquaculture, the method comprising:
- administering a composition comprising sialic acid or precursor thereof in an effective concentration to the fish under conditions such that infection by PRV and/or heart and skeletal muscle inflammation is treated.
A method for prophylaxis of infection by PRV, in fish in aquaculture, the method comprising:
- administering a composition comprising sialic acid or precursor thereof in an effective concentration to the fish under conditions such that infection by PRV and/or heart and skeletal muscle inflammation is inhibited.
A method for treating or inhibiting infection by Piscine Myocarditis Virus (PMV), in fish in aquaculture, the method comprising:
- administering a composition comprising sialic acid or precursor thereof in an effective concentration to the fish under conditions such that infection by PMV and/or cardiomyopathy syndrome is treated.
A method for prophylaxis of infection by PMV, in fish in aquaculture, the method comprising:
- administering a composition comprising sialic acid or precursor thereof in an effective concentration to the fish under conditions such that infection by PMV and/or cardiomyopathy syndrome is inhibited.
Sialic acid or precursor thereof for use in treating infection by ISAV in a fish in aquaculture.
Sialic acid or precursor thereof for use in prophylaxis of ISAV infection in a fish in aquaculture.
Sialic acid or precursor thereof for use in treating infection by SPDV in a fish in aquaculture.
Sialic acid or precursor thereof for use in prophylaxis of SPDV infection in a fish in aquaculture.
Sialic acid or precursor thereof for use in treating infection by sea lice in a fish in aquaculture.
Sialic acid or precursor thereof for use in prophylaxis of sea lice infection in a fish in aquaculture.
Sialic acid or precursor thereof for use in effecting a health parameter in an aquatic animal, the health parameter selected from the group consisting of:
- a) prophylaxis of infection by a sialic acid-binding virus;
- b) treatment of infection by a sialic acid-binding virus;
- c) amelioration of symptoms caused by sea lice infestation;
- d) improvement of skin barrier function by increasing sialic acid content in skin mucous;
- e) improvement of gut barrier function by increasing sialic acid content in gut mucous;
- f) increasing KDN content in the gut mucous;
- g) decreasing stress levels as evidenced by a decrease in lactate levels;
- h) treatment or prophylaxis of infection by Aeromonas salmonicida;
- i) treatment of symptoms of furunculosis;
- j) treatment or prophylaxis of infection by amoebas;
- k) stimulation of mucous epithelia cells;
- l) improvement in condition factor after smoltifying;
- m) improvement of growth after smoltifying;
- and
- n) improvement in length after smoltifying.
A method of improving a health parameter in an aquatic animal comprising administering to the aquatic animal sialic acid or a precursor thereof, the health parameter selected from the group consisting of:
- a) prophylaxis of infection by a sialic acid-binding pathogen;
- b) treatment of infection by a sialic acid-binding pathogen;
- c) amelioration of symptoms caused by sea lice infestation;
- d) improvement of skin barrier function by increasing sialic acid content in skin mucous;
- e) improvement of gut barrier function by increasing sialic acid content in gut mucous;
- f) increasing KDN content in the gut mucous;
- g) decreasing stress levels as evidenced by a decrease in lactate levels;
- h) stimulation of mucous epithelia cells;
- i) improvement in condition factor after smoltifying;
- j) improvement of growth after smoltifying;
- and
- k) improvement in length after smoltifying.
Dependencies are inferred from the claim text.