Broad-spectrum antiviral drugs

A method for treating a viral infection caused by a virus belonging to a taxon selected from Alphaherpesvirinae;

• Monodnaviria;
• Negarnaviricota;
• Pisuviricota;
• and Flavivirus;
• comprising administering a therapeutically effective amount of a compound, or a pharmaceutical composition comprising the compound, to a subject in need thereof, wherein the compound has a structure according to Formula (I), an enantiomer, a diastereoisomer, a hydrate, solvate, a crystal form, a tautomer, or a pharmaceutically acceptable salt thereof:
• wherein:
• L is, independently for each occurrence, optionally substituted C1-6 alkylene, wherein carbon atoms from two L groups can optionally form, together with Z1, part of an optionally substituted 4- to 8-membered carbocyclic or heterocyclic ring;
• Y is selected, independently for each occurrence, from O and NR7;
• Z1 is selected from bond, O, NR, CH2, CH(R), CH(R1), and CR(R1);
• R is selected from OH, optionally substituted C1-6 alkyl, NR7R8, and
• wherein n is 0 or 1;
• R1 is selected from OH, optionally substituted C1-6 alkyl, and NR7R8;
• R2, R3, R4, R5, and R6 are selected, independently for each occurrence, from H, halogen, OH, CN, NR7R8, C(O)NR7R8, and OR7, wherein at least one occurrence of R2, R3, R4, R5, or R6 is OH, and/or wherein at least two occurrences of R2, R3, R4, R5, or R6 form together part of an optionally substituted 4- to 8-membered heterocyclic ring containing 0;
• and
• R7 and R8 are selected, independently for each occurrence, from H and optionally substituted C1-6 alkyl.