Inhibin subunit beta e (inhbe) modulator compositions and methods of use thereof
AssigneeAlnylam Pharmaceuticals, Inc.
InventorAimee M. Deaton
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Abstract
The present invention relates to modulators, e.g., double stranded RNA (dsRNA) agents, antisense polynucleotide agents, antibodies, guideRNAs that effect ADAR editing, or guideRNAs that effect CRISPR editing, that modulate, e.g., inhibit, the expression and/or activity of inhibin subunit beta E (INHBE). The invention also relates to methods of using such modulators to inhibit expression and/or activity of INHBE and to methods of preventing and treating an INHBE-associated disorder, e.g., metabolic disorder, e.g., metabolic syndrome, in a subject.
Claims33
A modulator of inhibin subunit beta E (INHBE).
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