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US 2025/0051749 A1Published application
Novel promoter and use thereof
AssigneesToolgen Incorporated, Seoul National University R&Db Foundation
InventorsSu Cheong YEOM, Dong Woo SONG, Seokjoong KIM, Hye Kyung OH
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Abstract
The present application relates to a novel promoter and a use thereof. In one embodiment of the present application, provided is a nucleic acid construct comprising a novel promoter and a transgene of the present application. At this time, on the nucleic acid construct, the novel promoter of the present application can be operably linked to the transgene.
Claims16
A nucleic acid construct for expressing transgene comprising:
- a promoter comprising any one of the sequences of SEQ ID NOs:
- 01 to 08 and sequences having at least 80% sequence identity thereto;
- and
- a transgene,
- wherein the promoter is operably linked to the 5′ terminus of the transgene.
2 more elements
A nucleic acid construct for expressing transgene comprising:
- a promoter comprising any one of the sequences of SEQ ID NOs:
- 01 to 08 and sequences having at least 80% sequence identity thereto;
- a transgene;
- and
- an upstream homology arm designed to insert the promoter and the transgene into a target site within the genome of a cell;
- and
- a downstream homology arm designed to insert the promoter and the transgene into a target site within the genome of a cell,
- wherein the promoter is operably linked to the 5′ terminus of the transgene.
5 more elements
A nucleic acid construct for expressing transgene comprising:
- an upstream homology arm comprising a promoter comprising any one of the sequences of SEQ ID NOs:
- 01 to 08 and sequences having at least 80% sequence identity thereto;
- a transgene;
- and
- a downstream homology arm designed to insert the transgene into a target site on the genome of a cell,
- wherein the promoter is operably linked to the 5′ terminus of the transgene.
3 more elements
Dependencies are inferred from the claim text.