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US 2025/0051730 A1Published application
Cell culture media and methods for generating human alveolar macrophage-like cells
AssigneeTexas Biomedical Research Institute
InventorsLarry S. Schlesinger, Susanta Pahari
Life of this patent
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Abstract
Provided here methods of generating human alveolar macrophage-like cells in-vitro from blood-derived monocytes by culturing them in a cell culture medium containing a mixture of a surfactant and two or more cytokines. This mixture can contain calfactant, granulocyte-macrophage colony-stimulating factor, transforming growth factor beta, and interleukin-10.
Claims5
A cell culture medium for generating human alveolar macrophage-like (AML) cells from blood-derived monocytes, the cell culture medium comprising:
- a basal medium;
- and
- a mixture of a surfactant and two or more cytokines.
Dependencies are inferred from the claim text.