Systems and devices for producing biological products and methods of using the same

A modular assembly for processing one or more biological products, comprising:

• one or more single-use kits for one or more unit operations of a production process for the one or more biological products, the one or more single-use kits comprising one or more surge vessels and a plurality of flow channels;
• and
• a universal skid configured to couple with the one or more single-use kits, the universal skid comprising:
• a rigid support;
• and
• a plurality of flow-channel hardware sets mounted on the rigid support, each flow-channel hardware set configured to couple with a respective flow channel of the plurality of flow channels;
• wherein the plurality of flow-channel hardware sets allow for continuous processing over the one or more unit operations;
• and
• wherein at least one flow-channel hardware set of the plurality of flow-channel hardware sets includes components for supporting a first unit operation, and at least one flow-channel hardware set of the plurality of flow-channel hardware sets includes components supporting a second unit operation, the first and second unit operations being different.

A manufacturing system for processing one or more biological products, comprising:

• a plurality of modular assemblies coupled with each other, each modular assembly performing one or more unit operations, the plurality of modular assemblies allowing continuous processing within each of the plurality of modular assemblies, in between the plurality of modular assemblies, end-to-end continuous processing across the plurality of modular assemblies, and fully continuous processing across a plurality of unit operations, each modular assembly comprising:
• one or more single-use kits for the one or more unit operations, the one or more single-use kits comprising one or more surge vessels and a plurality of flow channels;
• and
• a universal skid configured to couple with the one or more single-use kits, the universal skid comprising:
• a rigid support;
• and
• a plurality of flow-channel hardware sets mounted on the rigid support, each flow-channel hardware set configured to couple with a respective flow channel of the plurality of flow channels,
• wherein the plurality of flow-channel hardware sets allow for continuous processing over the one or more unit operations;
• and
• wherein at least one flow-channel hardware set of the plurality of flow- channel hardware sets includes components for supporting a first unit operation, and at least one flow-channel hardware set of the plurality of flow-channel hardware sets includes components supporting a second unit operation, the first and second unit operations being different.