Methods for Treating Neurodegeneration Targeting IGF1/IGF1R
AssigneeThe Schepens Eye Research Institute, Inc.
InventorDong Feng Chen
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Abstract
Described are methods for the treatment of disorders associated with microglial activation, including neurodegenerative diseases and immunomodulatory diseases, particularly immunomodulatory diseases of the eye. Generally, the methods include administering a therapeutically effective amount of an IGF1 or IGF1R antibody or antigen binding fragment thereof, or an IGF1R agonist, as described herein, to a subject who is in need of, or who has been determined to be in need of, such treatment.
Claims11
A method for treating a neurodegenerative disease in a subject, the method comprising administering a therapeutically effective amount of an IGF1 or IGF1R antibody or antigen binding fragment thereof, or an IGF1R agonist.
A method for treating an immunomodulatory disease in a subject, the method comprising administering a therapeutically effective amount of an IGF1 or IGF1R antibody or antigen binding fragment thereof, or an IGF1R agonist.
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Dependencies are inferred from the claim text.