Humanized Anti-DNAM-1 Antibody
AssigneesUniversity of Tsukuba, TNAX Biopharma Corporation
InventorsAkira Shibuya, Kazuko Shibuya, Yumi Kanemaru, Fumie Abe
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Abstract
One aspect of the present invention is a humanized anti-DNAM-1 antibody or an antigen-binding fragment thereof, including: a heavy chain variable region containing an amino acid sequence of SEQ ID NO: 1 as HCDR1, an amino acid sequence of SEQ ID NO: 2 as HCDR2, and an amino acid sequence of SEQ ID NO: 3 as HCDR3; and a light chain variable region containing an amino acid sequence of SEQ ID NO: 4 as LCDR1, an amino acid sequence of SEQ ID NO: 5 as LCDR2, and an amino acid sequence of SEQ ID NO: 6 as LCDR3.
Claims10
A humanized anti-DNAM-1 antibody or an antigen-binding fragment thereof, comprising:
- a heavy chain variable region containing an amino acid sequence of SEQ ID NO:
- 1 as HCDR1, an amino acid sequence of SEQ ID NO:
- 2 as HCDR2, and an amino acid sequence of SEQ ID NO:
- 3 as HCDR3;
- and
- a light chain variable region containing an amino acid sequence of SEQ ID NO:
- 4 as LCDR1, an amino acid sequence of SEQ ID NO:
- 5 as LCDR2, and an amino acid sequence of SEQ ID NO:
- 6 as LCDR3.
Dependencies are inferred from the claim text.