Salt of 3,4-dihydroisoquinoline compound and use thereof
AssigneeCspc Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd.
InventorsXiaoshi Peng, Pengfei Li, Gengen Jin, Can Li, Min Yang, Xiaozheng Liu, Qiaoli Cui, Yajuan Si
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Abstract
Provided are a salt of a compound represented by formula (A), a solid form and a crystal form thereof, a pharmaceutical composition comprising same, the use thereof and a preparation method therefor. Compared with the compound represented by formula (A), a salt of the compound represented by formula (A) has higher solubility in water and a biological solvent medium, is easy to be prepared into a solid form, is convenient to transfer and weigh, and has good application prospects.
Claims19
A compound which is an inorganic acid addition salt or an organic acid addition salt of a compound represented by formula (A):
- wherein, the inorganic acid addition salt is a sulfate or phosphate, or the organic acid addition salt is selected from the group consisting of a malate, an oxalate, a succinate, a tartrate, an adipate, a citrate, a gluconate, a maleate, a fumarate, a lactate and a gentisate.
-3. (canceled)
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-21. (canceled)
Dependencies are inferred from the claim text.