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US 2025/0051246 A1Published application
Deuterated Antiviral Compounds
AssigneePfizer Inc.
InventorsKaren Jean COFFMAN, Dafydd Rhys OWEN, Matthew Richard REESE, Matthew Forrest SAMMONS, Raman SHARMA, Jamison Bryce TUTTLE, Qingyi YANG
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Abstract
The invention relates to compounds of Formula (I) wherein Y1a, Y1b, Y2a, Y2b, Y2c, Y2d, Y2e, Y2f, Y2g, Y2h and Y2i are as defined herein and to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes. The compounds of Formula (I) may be useful in the treatment of coronavirus infections and coronavirus infection related disorders.
Claims29
A compound of Formula (I)
- wherein
- Y1a, Y1b, Y2a, Y2b, Y2c, Y2d, Y2e, Y2f, Y2g, Y2h and Y2i are each independently H or D;
- provided that at least one of Y1a, Y1b, Y2a, Y2b, Y2c, Y2d, Y2e, Y2f, Y2g, Y2h and Y2i is D.
Dependencies are inferred from the claim text.