Systems and methods for delivery of therapeutic agents
AssigneeP Tech, LLC
InventorsPeter M. Bonutti, Justin E. Beyers, Tonya M. Bierman
Life of this patent
Estimating the term…
Abstract
An iontophoresis system includes a preloaded reservoir containing one or more doses of a therapeutic agent. As a result, the therapeutic agent does not have to be loaded into the reservoir prior to use. In such a system, the preloaded reservoir is generally disposable. Various components of the iontophoresis system can be combined with the reservoir in a disposable cartridge that is selectively connectable to other, reusable components of the iontophoresis system. In addition, the entire iontophoresis system can be formed from one or more disposable, one-time-use modules.
Claims20
An iontophoresis system for delivering a therapeutic agent to a subject, the iontophoresis system comprising:
- a support;
- an active electrode and an indifferent electrode configured to be connected to the support and configured to be in electrical communication with one another through a body portion of the subject, the active electrode configured to be selectively coupled to a power supply to generate a current extending through the body portion between the active electrode and the indifferent electrode;
- a controller configured to be operatively connected to the active electrode and the power supply to control an amount of power transmitted from the power supply to the active electrode to generate the current through the body portion;
- a reservoir preloaded with a therapeutic agent and configured to be connected to the support in operative alignment with the active electrode for delivering the therapeutic agent from an outlet of the reservoir into the body portion of the subject using an electromotive force of the current passing through the body portion;
- and
- a removable cover covering at least the outlet of the reservoir to contain the therapeutic agent within the reservoir until the covering is removed from the outlet.
A method of delivering a therapeutic agent to a body portion of a subject, the method comprising:
- removing a cover of an iontophoresis system extending over an outlet of a reservoir preloaded with a therapeutic agent;
- engaging, after said removing a cover, the iontophoresis system with the body portion of the subject so that the reservoir is operatively aligned with the body portion;
- and
- using a controller to convey power from a power supply to an active electrode of the iontophoresis system to draw a current through the body portion of the subject and deliver the preloaded therapeutic agent from the reservoir through the outlet and into the body portion of the subject using an electromotive force of the current.
Dependencies are inferred from the claim text.