US 2025/0050026 A1 · INJECTION SYSTEMS FOR DRUG DELIVERY WITH INTERNAL FORCE TRANSMISSION

Abstract

Injection systems for drug delivery are disclosed. A system may include a container filled or fillable with a drug, a stopper movably disposed in the container, a plunger, an energy source outputting a force, a mechanical linkage operable to transmit the force output by the energy source to the plunger to cause the plunger to act on the stopper to expel the drug from the container, and a trigger member. The system may have pre-injection state where the trigger member inhibits actuation of the mechanical linkage, an injection state where the trigger member permits actuation of the mechanical linkage, and a post-injection state where the plunger is stationarily positioned in an end-of-dose position. The system may be designed to limit the number of components included in various force transmission loops present in the pre-injection, injection, and/or post-injection states.

Claims21

Dependent claims

1-80. (canceled)

A system for injecting a drug, comprising:

an outer housing defining an interior space, the outer housing including a front portion, a rear portion, and a rearmost portion, wherein the front portion, the rear portion, and the rearmost portion are separate components rigidly connected to each other;
a container filled or fillable with the drug, at least a portion of the container being disposed in the interior space of the outer housing;
a stopper movably disposed in the container for expelling the drug from the container;
a plunger for acting on the stopper;
and
an energy source outputting or operable to output a force, at least a portion of the energy source being disposed in the interior space of the outer housing;
wherein at least the front portion of the outer housing is excluded from one or more force transmission loops such that at least the front portion of the outer housing is substantially free of any load caused by the force output by the energy source in the pre-injection state and/or the injection state, and
wherein two or more components disposed in the interior space of the outer housing are operably connected in series to define the one or more force transmission loops.

5 more elements

A system for injecting a drug, comprising:

an outer housing defining an interior space, the outer housing including a front portion, a rear portion, and a rearmost portion, wherein the front portion, the rear portion, and the rearmost portion are separate components rigidly connected to each other;
a container filled or fillable with the drug, at least a portion of the container being disposed in the interior space of the outer housing;
a stopper movably disposed in the container for expelling the drug from the container;
a plunger for acting on the stopper;
an energy source outputting or operable to output a force, at least a portion of the energy source being disposed in the interior space of the outer housing;
and
a mechanical linkage operable to transmit the force output by the energy source to the plunger to cause the plunger to act on the stopper to expel the drug,
wherein at least the front portion of the outer housing is excluded from one or more force transmission loops such that at least the front portion of the outer housing is substantially free of any load caused by the force output by the energy source in the pre-injection state and/or the injection state, and
wherein two or more components disposed in the interior space of the outer housing are operably connected in series to define the one or more force transmission loops.

6 more elements

Dependencies are inferred from the claim text.

Facts

Application

18/931,635Filed 30 Oct 2024

Priority

2 Oct 2018

Published

13 Feb 2025

Term ends

Not estimatedThe source records don’t support an estimate.

Classification13 codes

A61M 5/2033
Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically: spring-loaded one-shot…
A61M 5/31568
Means improving security or handling thereof: means keeping track of the total dose administered, e.g. since the cartridge was inserted
A61M 5/31585
The piston rod being moved by the rotational movement of a component directly in contact with it: the component being manually operated or…
A61M 5/14248
Adapted to be carried by the patient, e.g. portable on the body: of the skin patch type

Family

Application62/740,232Us provisional application · filed 2 Oct 2018

Application16/590,636Continuation · filed 2 Oct 2019

Application18/931,635Continuation

US 12,156,991 B2Related patent

US 2020/0101229 A1Published application

US 2025/0050026 A1This patent

From the US filing history. Foreign family members aren’t listed.

Injection systems for drug delivery with internal force transmission

Life of this patent

Injection systems for drug delivery with internal force transmission

Life of this patent

Abstract

Claims21