Encasement structures for implantable devices

A kit comprising:

• one or more encasement structures, each encasement structure comprising:
• at least one sheet comprising a bioscaffold material, the at least one sheet configured to define an internal region that is sized and shaped to hold an implantable medical device therein;
• and
• one or more depots comprising one or more active agents and a bioabsorbable material, wherein the one or more depots are configured to release the one or more active agents over a period of time;
• wherein the one or more encasement structures are configured to receive, and associate securely therewith, the one or more depots.

A method of reducing a risk of an adverse effect associated with implanting a medical device in a subject in need thereof, the method comprising:

• inserting the medical device into an encasement structure, the encasement structure comprising at least one sheet comprising a bioscaffold material, the at least one sheet configured to define an internal region that is sized and shaped to hold the medical device therein;
• applying one or more depots to the encasement structure to form an encased medical device;
• and
• implanting the encased medical device into the subject.