Absorbable Dressings for Sealing Sensitive Neural Tissue and Dura Matter
AssigneeEthicon, Inc.
InventorsSAI VERUVA, LEO B. KRIKSUNOV
Life of this patent
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Abstract
The present invention is directed to a sealant patch for use on or over sensitive tissue, comprising: a flat, flexible, bioresorbable substrate coated by a moisture-activated adhesive on one side thereof, wherein said adhesive is at least partially inactivated in a first portion of said patch, but remains active in peripheral areas surrounding the first portion. The adherence of the first portion to the tissue is weaker versus adherence in the peripheral areas. The adhesive in the first portion is fully or partially inactivated or pre-reacted prior to application of the sealant patch to the tissue.
Claims18
A tissue adhering sealant patch comprising:
- a) a flat, flexible, bioresorbable substrate having two major facing surfaces and
- b) a moisture-activated and tissue reactive adhesive having a measurable degree of tissue adhesion that has been applied onto at least one major facing surface, wherein
- 1) at least a first portion of the moisture-activated and tissue reactive adhesive has been at least partially deactivated,
- 2) while a second portion of the moisture-activated and tissue reactive adhesive
- (i) has not been deactivated and
- (ii) provides a desired degree of tissue adhesion between the substrate and at least a portion of a tissue surface that underlays the substrate which is located in proximity to a sensitive or compromised tissue surface that is covered by at least a portion of substrate having deactivated tissue reactive adhesive.
A kit comprising:
- a) a unified packaging;
- and, disposed inside said packaging
- (i) a flat, flexible, bioresorbable substrate coated by a moisture-activated tissue reactive adhesive on one side thereof, and
- (ii) a container of tissue reactive adhesive deactivating liquid configured for application onto at least a portion of the substrate.
Dependencies are inferred from the claim text.