Polysarcosine-vitamin e derivatives

Abstract

It relates to a polymer comprising a repeating sarcosine-based unit which is covalently attached directly or through a linker to a vitamin E-based moiety, acceptable salts, stereoisomers and mixtures thereof, and to conjugates of formula (II) comprising these polymers. Nutraceutical, pharmaceutical, diagnostic and cosmetic compositions comprising the polymers and/or the conjugates of formula (II), together with acceptable excipients or carriers are also provided, as well as self-assembled particles comprising the polymers and/or the conjugates of formula (II) and optionally agents encapsulated within the self-assembled particles. It also relates to the use of the polysarcosine-vitamin E derivatives and/or their conjugates in medicine and diagnostics, and as solubilizers, absorption and permeation enhancers, emulsifiers or surface stabilizers.

Dependencies are inferred from the claim text.