Anti-fibrous cells, medicament comprising the cells, and method for obtaining these cells
OwnerMassimo Dominiciinventor
Life of this patent
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Abstract
A method to produce modified mesenchymal cells, in particular for the treatment of renal fibrosis, includes modifying the cells with a viral vector, in such a way that the modified cells code for a protein which is Decorin. The modified mesenchymal cells are modified with a modifying agent that includes a viral vector associated with the mesenchymal cells so that the modified mesenchymal cells express Decorin. A medicament, in particular for the treatment of renal and lung fibrosis, includes the mesenchymal cells modified with the modifying agent and which express Decorin.
Claims17
Mesenchymal cells modified with a modifying agent for use in the treatment of fibrosis of lungs or kidney, wherein said modifying agent comprises a viral vector that codes for Decorin infecting said mesenchymal cells and that the infected mesenchymal cells express Decorin.
Dependencies are inferred from the claim text.