Pharmaceutical composition for preventing or treating cancer, comprising sglt-2 inhibitor and gossypol
AssigneeHaim Bio Co., Ltd.
InventorsYong Baeg Kim, Sun Young Park, Se Young Jeong, Hong Yeoul Kim
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Abstract
The present invention relates to a pharmaceutical composition for co-administration for effectively preventing or treating cancer. The pharmaceutical composition of the present invention is applicable to various cancer types, and the effect of killing cancer cells and/or cancer stem cells is significantly improved when the active ingredients of the composition are administered in combination compared to when the active ingredients are administered alone. Thus, the pharmaceutical composition is expected to be widely used for cancer treatment in the medical and health fields.
Claims25
A pharmaceutical composition for preventing or treating cancer containing gossypol, a biguanide-based compound, and a sodium-glucose cotransporter-2 inhibitor or a pharmaceutically acceptable salt thereof as an active ingredient.
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The pharmaceutical composition of claim 16, wherein the biguanide-based compound is any one or more selected from the group consisting of phenformin, metformin, and buformine.
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A food composition for preventing or ameliorating cancer containing gossypol, a biquanide-based compound, and a sodium-glucose cotransporter-2 inhibitor or a pharmaceutically acceptable salt thereof as an active ingredient.
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A method for preventing or treating cancer, comprising a step of administering to a subject in need thereof a pharmaceutically effective amount of gossypol, a biguanide-based compound, and a sodium-glucose cotransporter-2 inhibitor or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.