Methods of treating pancreatic cancer by using bet inhibitor and parp inhibitor
AssigneeNational Cheng Kung University
InventorsYan-Shen SHAN, Wen-Pin SU, Ya-Chin HOU
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Abstract
Disclosed herein is a method of treating a pancreatic cancer in a subject who is responsive to a platinum-based therapy. The method comprises administering to the subject an effective amount of a BET inhibitor and an effective amount of a PARP inhibitor. According to some embodiments of the present disclosure, the BET inhibitor is mivebresib, JQ1, or AZD5153, and the PARP inhibitor is rucaparib, veliparib, or olaparib.
Claims9
A method of treating a pancreatic cancer in a subject who is responsive to a platinum-based therapy, comprising administering to the subject an effective amount of a BET inhibitor and an effective amount of a PARP inhibitor.
Dependencies are inferred from the claim text.