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US 2025/0049785 A1Published application
Methods for the treatment of glioblastoma that minimize radiation damage in susceptible patients
AssigneeRhode Island Hospital
InventorEric T. Wong
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Abstract
The embodiments of the present invention provide methods for the treatment of glioblastoma that minimize radiation damage in susceptible patients, such as the elderly. Patients with one or more diagnostic marker of α-synucleinopathy, or other markers of CNS degeneration, receive a modified treatment regimen that minimizes the risk for accelerated encephalopathy or myelopathy from radiation.
Claims9
A method of preventing or minimizing radiation damage in a subject afflicted with a glioblastoma tumor, comprising:
- (i) determining the presence or absence of one or more diagnostic marker of α-synucleinopathy or other markers of central nervous system (CNS) degeneration;
- and
- (ii) treating a subject with one or more diagnostic marker of α-synucleinopathy or other markers of CNS degeneration, with a modified treatment regimen that minimizes the risks associated with the standard Stupp protocol.
Dependencies are inferred from the claim text.