Methods of treating prostate cancer or metastasized prostate cancer
AssigneeZetagen Therapeutics, Inc.
InventorBryan S. Margulies
Life of this patent
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Abstract
A composition is provided for treating a cancer which includes a high concentration of an OGFR antagonist in a formulation that may also include collagen and calcium phosphate. The composition is useful for treating a cancer when locally administered at a site of cancer in a patient.
Claims9
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A method of decreasing volume of a prostate cancer tumor comprising locally administering by introduction into the prostate cancer tumor of a subject in need thereof with a single injection a therapeutically effective amount of a composition comprising from about 3.2 mg/ml to about 5.2 mg/ml of naloxone or a salt thereof, iron (III) sulfate, calcium phosphate, and collagen, wherein the administration of the composition in a single injection decreases the volume of the prostate cancer tumor by about two-fold after 14 days compared to a phosphate-based bone cement infused with 0.9% normal saline.
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Dependencies are inferred from the claim text.