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US 2025/0049783 A1Published application
Opioid formulations
AssigneeCamurus AB
InventorsFredrik Tiberg, Ian Harwigsson, Markus Johnsson
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Abstract
A depot precursor formulation comprising: a) a controlled-release matrix; b) at least oxygen containing organic solvent; c) at least 12% by weigh of at least one active agent selected from buprenorphine and salts thereof, calculated as buprenorphine free base. Corresponding depot compositions and methods of treatment in pain management, by opioid maintenance and related methods are provided.
Claims11
1-30. (canceled)
A method of treating opioid dependence in a patient, the method comprising administering to the patient a composition comprising:
- about 5% by weight of buprenorphine;
- about 10% by weight of ethanol;
- about 42% by weight of phosphatidylcholine;
- and
- about 42% by weight of glycerol dioleate,
- wherein the composition is administered once weekly from a pre-filled syringe, and
- wherein the patient has previously received buprenorphine.
4 more elements
Dependencies are inferred from the claim text.