Compound and use thereof in preparation of medicament for treating alzheimer's disease
OwnerTao Suninventor
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OwnerTao Suninventor
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The present disclosure relates to a compound and the use thereof in the preparation of a medicament for treating Alzheimer's disease. The present disclosure provides a method for constructing an animal model of diseases with N-oleoyl-dopamine (OLDA) and the use of the model in drug screening and animal experimental research, wherein the animal model includes at least one of an animal model of neurodegenerative diseases, an animal model of intestinal permeability diseases, and an animal model of inflammatory diseases. The present disclosure is based on the discovery that OLDA has a new use for a neurodegenerative disease, an intestinal permeability disease, and an inflammatory disease, and based on OLDA, compounds that have a therapeutic effect on the above diseases are identified.
A method for constructing an animal model of diseases, wherein the method comprises administering an effective dose of N-oleoyl-dopamine to an animal;
A method for preventing or treating a disease in an animal, wherein the method comprises administering an effective dose of a compound or a pharmaceutically acceptable salt, hydrate, solvate, racemate, enantiomer, diastereomer, or polymorph thereof to the animal;
Dependencies are inferred from the claim text.