Method for amplifying expression of transporter-related gene in epidermal cells
AssigneeJ-Network, Inc.
InventorsTatsuro MIYOSHI, Brian Charles KELLER, Akira KODAMA
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Abstract
An action of amplifying expression of transporter-related genes in epidermal cells by a diacylglycerol PEG adduct is utilized. A method for amplifying expression of transporter-related genes in epidermal cells is provided. The method comprises applying a diacylglycerol PEG adduct, wherein the diacylglycerol PEG adduct is at least one of a group consisting of PEG-12 glycerol dimyristate (GDM12), PEG-12 glycerol distearate (GDS12), PEG-23 glycerol distearate (GDS23), PEG-23 glycerol dipalmitate (GDP23), and PEG-12 glycerol dioleate (GDO12).
Claims6
A method for amplifying expression of a transporter-related gene in epidermal cells, the method comprising applying a diacylglycerol PEG adduct having a following structural formula;
- in which number of carbon atoms of R in a long-chain fatty acid is in a range of 11 to 23 and n in a polyethylene glycol chain is in a range of 11 to 46,
- wherein the diacylglycerol PEG adduct is at least one of a group consisting of PEG-12 glycerol dimyristate (GDM12), PEG-12 glycerol distearate (GDS12), PEG-23 glycerol distearate (GDS23), PEG-23 glycerol dipalmitate (GDP23), and PEG-12 glycerol dioleate (GDO12).
A method for using an active ingredient for amplifying expression of a transporter-related gene in epidermal cells in a cosmetic or a skin external preparation, the method comprising using, as the active ingredient, a diacylglycerol PEG adduct having a following structural formula;
- in which number of carbon atoms of R in a long-chain fatty acid is in a range of 11 to 23 and n in a polyethylene glycol chain is in a range of 11 to 46,
- wherein the diacylglycerol PEG adduct is at least one of a group consisting of PEG-12 glycerol dimyristate (GDM12), PEG-12 glycerol distearate (GDS12), PEG-23 glycerol distearate (GDS23), PEG-23 glycerol dipalmitate (GDP23), and PEG-12 glycerol dioleate (GDO12).
Dependencies are inferred from the claim text.