Back to results
US 2025/0049680 A1Published application
Compositions and methods for treating dentin caries
AssigneeRutgers, The State University of New Jersey
InventorMohammad Ali SAGHIRI
Life of this patent
Estimating the term…
Abstract
The present disclosure provides for oral compositions and method of using the same for treating dentin using an orally acceptable salt which includes a divalent metal cation and an anionic counterion, such as an ascorbic acid phosphate counterion and a silane coupling agent. The methods provide for remineralization and reinforcing of dentin by doping with the divalent cation, thereby preventing and/or reducing the occurrence of dental caries
Claims20
An oral composition comprising:
- (i) an effective amount of an orally acceptable salt comprising
- an orally acceptable divalent metal cation and an anionic counterion,
- wherein the anionic counterion comprises
- an ascorbic acid phosphate counterion;
- and
- (ii) a silane coupling agent.
3 more elements
A method for treating a dentin, the method comprising:
- contacting the dentin with an oral composition comprising
- (i) an effective amount of an orally acceptable salt comprising
- an orally acceptable divalent metal cation and an anionic counterion,
- wherein the anionic counterion comprises
- an ascorbic acid phosphate counterion;
- and
- (ii) a silane coupling agent;
- allowing the oral composition to remain in contact with the dentin for a predetermined duration;
- and
- rinsing the dentin,
- wherein the treatment results in at least one of the following:
- remineralization of the dentin, improvement of surface microhardness, increase in diametral tensile strength (DTS), increase in compressive strength of the dentin compared to untreated dentin or any combination thereof.
9 more elements
Dependencies are inferred from the claim text.