Repositionable tissue capture system, device and method

A device for treating tissue, comprising:

• a tissue capture assembly removably attachable to an insertion device configured to be inserted to a target site within a living body, the tissue capture assembly including a tissue capture sleeve that, in an initial configuration, is removably received on a distal end of the insertion device and a flange that is removably mountable on the insertion device proximal of the tissue capture sleeve when the tissue capture sleeve is in the initial configuration;
• a first hollow member extending from a proximal end that remains, during use, outside the body accessible by a user to a distal end coupled to the flange;
• a first tube slidably received within the first hollow member and extending from a proximal end that remains, during use, outside the body accessible by the user distally beyond the flange to a first tube distal end, the first tube being configured to push the tissue capture sleeve distally off of the insertion device when the first tube is advanced distally through the first hollow member;
• and
• a first control member slidably received within the first tube and extending from a proximal end that remains, during use, outside the body accessible by the user to a distal end forming a first loop coupled around a circumference of a distal opening of the tissue capture sleeve, the first loop being configured to move between a constricted configuration in which at least a portion of the first loop is drawn proximally into the first tube and an open configuration in which the first loop is extended distally from the first tube to open the first loop and the distal opening of the tissue capture sleeve.

A device for treating tissue, comprising:

• a catheter including a tissue capture assembly mounted on a distal portion thereof, the tissue capture assembly including a tissue capture sleeve that, in an initial configuration, is removably received on a distal end of the catheter and a flange extending radially outward from an exterior of the catheter proximal of the tissue capture sleeve when the tissue capture sleeve is in the initial configuration;
• a first hollow member extending from a proximal end that remains, during use, outside a living body accessible by a user to a distal end coupled to the flange;
• a first tube slidably received within the first hollow member and extending from a proximal end that remains, during use, outside the body accessible by the user, distally beyond the flange to a first tube distal end;
• and
• a first control member slidably received within the first tube and extending from a proximal end that remains, during use, outside the body accessible by the user to a distal end forming a first loop coupled around a circumference of a distal opening of the tissue capture sleeve, the first loop being configured to move between a constricted configuration in which at least a portion of the first loop is drawn proximally into the first tube and an open configuration in which the first loop is extended distally from the first tube to open the first loop and the distal opening of the tissue capture sleeve.

A method for capturing tissue, comprising:

• inserting into a living body to a target site adjacent to the tissue to be treated, a tissue capture assembly removably attached to an insertion device with the tissue capture assembly including a tissue capture sleeve removably received on a distal end of the insertion device and a flange removably mountable on the insertion device proximal of the tissue capture sleeve, wherein the tissue capture sleeve is coupled to a first control member slidably received within a first tube with a first loop at the distal end of the first control member being coupled around a distal opening of the tissue capture sleeve;
• drawing a target portion of the tissue toward a distal end of the insertion device;
• moving the first tube distally to push the tissue capture sleeve distally off the insertion device so that the target portion of the tissue is received within the tissue capture sleeve;
• drawing the first control member proximally into the first tube to cinch the first loop closed over a portion of the tissue adjacent to the target portion of the tissue until the first loop closes the distal opening of the tissue capture sleeve;
• and
• when a user determines that a portion of the tissue captured within the tissue capture sleeve has been captured as desired, drawing the first control member further proximally into the first tube to sever the target portion of the tissue from a surrounding portion of the tissue.