Suture closure devices

A closure device for suturing a puncture, the closure device comprising:

• first and second sutures;
• first and second ferrules, coupled to respective distal end portions of the first and the second sutures;
• an elongate support, which comprises one or more shafts;
• a suture-positioning support, which is (a) coupled to a distal end portion of the elongate support, (b) laterally extendable with respect to the elongate support, and (c) shaped so as to define a ferrule receptacle, which is configured to removably receive the first and the second ferrules, one at a time;
• first and second ferrule-advancing suturing needles, which are removably couplable to the first and the second ferrules, respectively;
• and
• first and second ferrule-withdrawing suturing needles, which are removably couplable to the first and the second ferrules, respectively,
• wherein the closure device is configured to direct the first ferrule into the ferrule receptacle during distal advancement of the first suturing ferrule-advancing needle removably coupled to the first ferrule,
• wherein the closure device is configured to direct the first ferrule-withdrawing suturing needle to the first ferrule during distal advancement of the first ferrule-withdrawing suturing needle,
• wherein the closure device is configured such that after the distal advancement of the first ferrule-withdrawing suturing needle to the first ferrule, proximal withdrawal of the first ferrule-withdrawing suturing needle coupled to the first ferrule removes the first ferrule from the ferrule receptacle,
• wherein the closure device is configured to direct the second ferrule into the ferrule receptacle during distal advancement of the second suturing ferrule-advancing needle removably coupled to the second ferrule, wherein the closure device is configured to direct the second ferrule-withdrawing suturing needle to the second ferrule during distal advancement of the second ferrule-withdrawing suturing needle, and
• wherein the closure device is configured such that after the distal advancement of the second ferrule-withdrawing suturing needle to the second ferrule, proximal withdrawal of the second ferrule-withdrawing suturing needle coupled to the second ferrule removes the second ferrule from the ferrule receptacle.