Continuous analyte monitoring system with microneedle array

A sensing device comprising a single microneedle array for use in sensing an analyte, the single microneedle array comprising:

• a first microneedle comprising a first working electrode comprising a first biorecognition element configured to react with the analyte;
• a second microneedle comprising a second working electrode comprising a second biorecognition element configured to react with the analyte;
• and,
• a third microneedle comprising a counter electrode,
• wherein the first microneedle, the second microneedle, and the third microneedle are insulated and electrically isolated from one another such that the first working electrode and the second working electrode provide independent measurements of the analyte.

A method for sensing an analyte via a microneedle array, comprising:

• applying a first bias potential between a first working electrode on a first microneedle formed from a semiconductor substrate and a reference electrode, wherein the first working electrode comprises a first biorecognition element;
• applying a second bias potential between a second working electrode on a second microneedle formed from the semiconductor substrate and the reference electrode, wherein the second working electrode comprises a second biorecognition element;
• measuring a first current value between the first working electrode and a counter electrode, the first current value being proportional to a concentration of the analyte;
• and
• measuring a second current value between the second working electrode and the counter electrode, the second current value being proportional to a concentration of the analyte,
• wherein each of the first microneedle and the second microneedle are insulated from the semiconductor substrate and electrically isolated from one another such that the first current value and the second current value are independent of one another.