Gel electrophoresis diagnostic kit and methods of using the same
AssigneeVital Biosciences Inc.
InventorsMounir A. KOUSSA, Calvin DOMENICO, Ronald L. GREEN, Joshua John FORMAN, Andrew WARD, Lisa CALDWELL
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Abstract
An electrophoretic device for detecting biomarkers in collected bodily fluid and methods of using the same.
Claims38
A biomarker detector cartridge comprising:
- a cartridge body;
- a fluid collector coupled to the cartridge body configured to collect a fluid comprising a biomarker;
- an electrophoretic cell coupled to the cartridge body and comprising a separation medium;
- and
- a nanoswitch source disposed in the cartridge body and configured to contact the fluid.
The biomarker detector cartridge of any one of the preceding claims, wherein the nanoswitch source comprises a DNA nanoswitch configured to bind the biomarker.
The biomarker detector cartridge of any one of the preceding claims, wherein the nanoswitch source comprises a plurality of nanoswitch sources.
The biomarker detector cartridge of any one of the preceding claims, wherein the fluid collector comprises a sponge.
The biomarker detector cartridge of any one of the preceding claims, wherein the separation medium comprises a viscous solution or a gel.
The biomarker detector cartridge of any one of the preceding claims, wherein the electrophoretic cell comprises a stain.
The biomarker detector cartridge of any one of the preceding claims, wherein the electrophoretic cell comprises electrical contacts.
The biomarker detector cartridge of any one of the preceding claims, wherein the fluid comprises a bodily fluid.
The biomarker detector cartridge of any one of the preceding claims, comprising a cap configured to cover the fluid collector before fluid collection or after fluid collection.
The biomarker detector cartridge of any one of the preceding claims, comprising a cap configured to compress the fluid collector after fluid collection to direct collected fluid to the electrophoretic cell.
The biomarker detector cartridge of any one of the preceding claims, wherein the nanoswitch source comprises a sticker, a capsule, a pellet, or a residue.
The biomarker detector cartridge of any one of the preceding claims, comprising a test result indicator coupled to the electrophoretic cell.
Dependencies are inferred from the claim text.