Reinforced double-threaded slide-ring networks for accelerated hydrogel discovery and 3d-printing

A sensor, wherein the sensor comprises a composition comprising:

• a plurality of macrocyclic rings and a plurality of polymers,
• wherein the polymers are covalently appended to one or more macrocycle-binding molecules,
• wherein each of the plurality of macrocyclic rings comprises a cavity,
• wherein the cavities of the plurality of macrocyclic rings are threaded onto the polymers,
• wherein at least some of the threaded macrocyclic rings are individually threaded onto two polymers to form double-threaded macrocyclic rings,
• wherein the double-threaded macrocyclic rings comprise a plurality of different segments, and
• wherein the plurality of different segments associate with one another to form a crystalline network.

A method of manufacturing a three-dimensional structure, said method comprising:

• applying a composition onto a surface, wherein the composition comprises:
• a plurality of macrocyclic rings and a plurality of polymers,
• wherein the polymers are covalently appended to one or more macrocycle-binding molecules,
• wherein each of the plurality of macrocyclic rings comprises a cavity,
• wherein the cavities of the plurality of macrocyclic rings are threaded onto the polymers,
• wherein at least some of the threaded macrocyclic rings are individually threaded onto two polymers to form double-threaded macrocyclic rings,
• wherein the double-threaded macrocyclic rings comprise a plurality of different segments, and
• wherein the plurality of different segments associate with one another to form a crystalline network;
• wherein the applying results in the formation of the three-dimensional structure on the surface.

A method of forming a rotaxane composition, said method comprising:

• covalently appending one or more macrocycle-binding molecules onto a plurality of polymers,
• threading a plurality of macrocyclic rings onto the plurality of polymers,
• wherein each of the plurality of macrocyclic rings comprises a cavity,
• wherein the plurality of macrocyclic rings are threaded onto the polymers through the cavities,
• wherein at least some of the threaded macrocyclic rings become individually threaded onto two polymers to form double-threaded macrocyclic rings,
• wherein the double-threaded macrocyclic rings comprise a plurality of different segments, and
• wherein the plurality of different segments associate with one another to form a crystalline network.