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US 2025/0042880 A1Published application
Diaminobutoxy-substituted isoflavonoids as mitochondrial complex i inhibitors for cancer treatment
AssigneeUniversity of Kentucky Research Foundation
InventorsChunming Liu, David Watt, Xifu Liu
Life of this patent
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Abstract
The presently-disclosed subject matter relates to diaminobutoxy-substituted isoflavonoids and their use thereof as mitochondrial complex I inhibitors for the treatment of cancer.
Claims11
A compound having a structure according to Formula I, and salts thereof:
- wherein R1 is heterocycloalkyl or secondary aminoalkyl;
- wherein each of R2, R3, and R4 is independently selected from the group consisting of H, halo, and alkoxy;
- and
- wherein n is from 1 to 10.
1 more element
Dependencies are inferred from the claim text.