Gamma-polyglutamic acid and zinc compositions
AssigneeXylonix Pte. Ltd.
InventorJinhyuk Fred Chung
Life of this patent
Estimating the term…
Abstract
The invention relates to compositions for administering zinc, including nutritional supplement compositions, comprising γ-polyglutamic acid, a zine salt, and a gastro-resistant material for use as a dietary supplement to provide zinc to persons desiring or in need thereof, and methods for preparing such compositions as solid dosage forms such as tablets and capsules, and as liquid dosage forms.
Claims14
1-7. (canceled)
A method for preparing a solid dosage form comprising γ-polyglutamic acid, a zinc salt, and a gastro-resistant outer coating, said method comprising:
- (a) mixing together γ-polyglutamic acid having a number average molecular weight in the range of about 5 kDa to about 300 kDa, the zinc salt, wherein the amount of said zinc salt provides about 1 mg to about 75 mg of zinc per solid dosage form, one or more filler, one or more binder, and optionally one or more disintegrant;
- (b) granulating the mixture obtained in step (a) using a wet granulation process to obtain a granulated mixture;
- (c) mixing a lubricating agent and optionally a glidant with the granulated mixture obtained in step (b);
- (d) tableting the mixture obtained in step (c) to obtain tablets;
- (e) coating the tablets obtained in step (d) with a gastro-resistant outer coating, whereby the solid dosage form is obtained.
A method for preparing a solid dosage form comprising γ-polyglutamic acid, a zinc salt, and a gastro-resistant binder, said method comprising:
- (a) mixing together γ-polyglutamic acid having a number average molecular weight in the range of about 5 kDa to about 300 kDa, the zinc salt, wherein the amount of said zinc salt provides about 1 mg to about 75 mg of zinc per solid dosage form, the gastro-resistant binder, one or more filler, optionally one or more binder other than the gastro-resistant binder, and optionally one or more disintegrant;
- (b) granulating the mixture obtained in step (a) using a wet granulation process to obtain a granulated mixture;
- (c) mixing a lubricating agent and optionally a glidant with the granulated mixture obtained in step (b);
- (d) tableting the mixture obtained in step (c) to obtain tablets;
- (e) optionally coating the tablets obtained in step (d), whereby the solid dosage form is obtained.
12-22. (canceled)
Dependencies are inferred from the claim text.